ISSN: 1300-0365
Dil: Türkçe
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Diode Lazer Lezyonlannın Karşılaştırmalı Histopatolojisi: Ultrastrüktür Ve Teorik Termal Hasar Profilleri
Tongalp H. TEZEL *, İlhan GÜNALP**, Gülgün TEZEL*, Aysel ŞEFTALİOĞLU***, Belma AlABAY**** * Ankara Numune Hastanesi 2. Göz Kliniği Başasistanı **Prof.Dr.Ankara Ü. T.F. Göz Hast ABD. ***Prof.Dr. HacettepeÜ.T.F. Histoloji-Embriyoloji BD ****Doç. Dr. Ankara ÜTF Histoloji-Embriyoloji BD, ANKARA
THE COOPERATIVE HISTOPATHOLOGY OF DIODE USER LESIONS: ULTRASTRUCTURE
AND THEORETICAL THERMAL INJURY PROFILES
A comparative histopathological study of semiconductor diode, argon, dye yellow and dye red laser spots was conducted by light
and electron microscopy. Six eyes of three Chincilla rabbits were evaluated by clinicopathologic correlation to up to 8 weeks after
laser treatment. Ophthalmoscopically similar lesions that are obtained in humans during panretinal photocoagulation were obtained
by using comparable irridiance levels of 255 W/cm2, and 2290 W/cm2, for 100 and 300 micrometers spot size respectively. Retinal
photocoagulation with the diode laser required 1.75-2.00 times more power than with the argon laser to create ophtalmoscopically
similar lesions. Damage was confined to the outer retina, retinal pigment epithelium and choroid with diode laser irradiation.
This was in contrast to the appearances seen following the photocoagulation with other lasers. The findings of the histopathological
study were evaluated on a computerized laser thermal simulation model. A high amount of heat production and thus, a great
chance of permanent tissue destruction is demonstrated by using laser photocoagulators other than the diode laser. Similar to the
animal model, calculations regarding to the parameters of human studies also revealed that the diode laser can be safely used in
the treatment of macular diseases. [Oftalmoloji 1993; 2(2): 184-200]Keywords: Diode laser. Retinal photocoagulation, Thermal damage, Computerized analysis
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