ISSN: 1300-0365 Dil: Türkçe
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Pulsatile Ocular Blood Flow Changes In Isoflurane Anesthesia
Hikmet Başmak*, Birgül BüyükkIdan**, Sacit Güleç***,Etihan Cantürk****, Nilgün YIldIrIm*****
* Yrd.Doç.Dr.,Osmangazi Üniversitesi Tıp Fakültesi Göz Hast. AD, Öğr. Üy.,** Yrd.Doç.Dr.,Osmangazi Üniversitesi Tıp Fakültesi Anestezi ve Reanimasyon AD, Öğr. Üy.,*** Doç.Dr.,Osmangazi Üniversitesi Tıp Fakültesi Anestezi ve Reanimasyon AD, Öğr. Üy.,**** Uz.Dr.,Eskişehir Devlet Hastahanesi,***** Prof.Dr.,Osmangazi Üniversitesi Tıp Fakültesi Göz Hast. AD, Öğr. Üy., ESKİŞEHİR To investigate the influence of the isoflurane anesthesia on pulsatile ocular blood flow (POBF), we conducted a prospective study in 23 patients with no ocular abnormality. POBF and IOP were measured with a pneumotonometer in isoflurane anesthesia. POBF, IOP, systemic blood pressure, heart rate and peripheric O2 saturation were measured prior to anesthesia, after the administration of the tiopental, vecuronium, entubation and during isoflurane application in 30th and 90th minutes and fifteen minutes after complete recovery from anesthesia.
Soon after thiopental, POBF and IOP decreased significantly (p<0.05). After vecuronium, the decreased level of the POBF and IOP was reserved. On the other hand, after entubation, POBF and IOP showed significant increase when compared to the base-line limit (p<0.05). During the isoflurane anesthesia, IOP was found to be decrease to base-line limit. Yet that decrease was not statistically significant. Besides, POBF decreased below the normal limit (p<0.05). Therefore caution must be taken when isoflurane anesthesia is applied on patients with retinal and optic disc circulatory disturbances.Keywords: Pulsatile ocular blood flow,
Intraocular pressure, general anesthesia,
Thiopental, vecuronium, IsofluraneTurkiye Klinikleri J Ophthalmol 1998, 7:84-87
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