ISSN: 1300-0365
Dil: Türkçe
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Tear Film Studies In Rheumatoid Arthritis Patients
Mustafa ÇELİKEL*, Kemal GÜNDÜZ**, Süleyman OKUDAN***, Nazmi ZENGİN****, Ahmet ÖZKAĞNICI*
* Uz.Dr.,Selçuk Üniversitesi Tıp Fakültesi Göz Hastalıkları AD,** Prof.Dr.,Selçuk Üniversitesi Tıp Fakültesi Göz Hastalıkları AD,*** Doç.Dr.,Selçuk Üniversitesi Tıp Fakültesi Göz Hastalıkları AD,**** Yrd.Doç.Dr.,Selçuk Üniversitesi Tıp Fakültesi Göz Hastalıkları AD, KONYA
The most common ophthalmological sign of rheumatoid arthritis (RA) is keratoconjunctivitis sicca (KCS). In this study, KCS was investigated in 76 eyes of 38 patients with RA. The tear function tests used were Schirmer-1, tear film break up time and rose bengal (RB) staining tests. These tests can be carried out easily in the outpatient service, without the need of laboratory conditions.
In this study, KCS was diagnosed in 39.47 % of the patients with RA and the diagnostic sensitivity of the tests were investigated in KCS. In addition, the diagnostic spesificity ratio of the tests were determined in 46 eyes of 23 subjects in the control group. There was no statistically significant difference between the control group and the patients with RA in terms of age and sex distribution (p>0.05). Tear film break up time test was the most sensitive test with 90% sensitivity, while its specificity (76%) was significantly lower than that of the other two tests (p<0.05). The most spesific test was the RB staining test with a 95.65% of specificity. However, the sensitivity (66.66%) of this test was significantly lower than that of the other two tests (p<0.05). With combined usage of these tests, higher specificity and sensitivity can be obtained which is an important leading factor for accurate diagnosis.Keywords: Rheumatoid arthritis,
keratoconjonctivitis sicca, tear filmTurkiye Klinikleri J Ophthalmol 1998, 7:124-127
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