ISSN: 1300-0365
Dil: Türkçe
|
|
|
The Effect Of Dorzolamide On Intraocular Pressure
Mustafa Kemal ArIcI*, Ayşen Topalkara*, Cenap Güler**
* Yrd.Doç.Dr.,Cumhuriyet Üniversitesi Tıp Fakültesi Göz Hastalıkları AD,** Prof.Dr.,Cumhuriyet Üniversitesi Tıp Fakültesi Göz Hastalıkları AD, Sİvas
The present study was undertaken to investigate the effect of topical carbonic anhydrase inhibitor, dorzolamide hydrochloride, on intraocular pressure (IOP) with plasebo control. Twenty eight patients with primary open-angle glaucoma whose IOP greater than 22mmHg were included in the study. Before beginning the study diurnal IOP curves were obtained and then three times daily, for 5 days Dorzolamide or plasebo was administrated. On the first and fifth day diurnal IOP measured. It was found that maximum decreases of IOP were 23.3% on the first day, 22.9% on the 5th day. The results for plasebo were 1.3% and 8.9% respectively. The differences were statistically significant(p<0.01). As a result, the use of 2% dorzolamide three times a day could decrease IOP and it could be used in the treatment of glaucoma.Keywords: Dorzolamide, Intraocular pressure,
Primary open-angle glaucomaTurkiye Klinikleri J Ophthalmol 1998, 7:175-177
|
|
|
|
|
