ISSN: 1300-0365
Dil: Türkçe
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The Effect Of Intraocular Pressure (iop) Control Level To Glaucomatous Damage Progression In Primary Open Angle Glaucoma (poag)
Tamer ARIKAN*, Serap Özden**, Volkan YaylalI***, Cem YIldIrIm***, Hüseyin Karadavut*
* Uz.Dr., Pamukkale Üniversitesi Tıp Fakültesi Göz Hastalıkları AD,** Doç.Dr., Pamukkale Üniversitesi Tıp Fakültesi Göz Hastalıkları AD,*** Yrd.Doç.Dr., Pamukkale Üniversitesi Tıp Fakültesi Göz Hastalıkları AD, DENİZLİ
In our study the effect of intraocular pressure (IOP) level to glaucomatous damage progression was studied in primary open angle glaucoma (POAG) subjects who received either medical or surgical treatment.
51 eyes of 28 subjects who received the diagnosis of POAG in the department of Ophthalmology, Pamukkale University Medical School, between the dates of January 1995 and January 1996 and treated for the first time in this clinic were studied. Subjects were evaluated in two groups as group 1 who had IOP of 17 or below and group 2 who had IOP of 18 to 21 mmHg. Subjects were followed at least for 20 months. Optic nerve head changes and visual field mean deviation (MD) values were evaluated.
No significant optic nerve head change was observed between the 2 groups. By using linear regression analysis for MD changes, the progression was obtained in 3 (11.1 %) eyes in group 1 and the mean change ratio was -0,82 [(-0,72), (-0,94)] dB/ year (95% confıdence interval) in these eyes. The progression was detected in 7 (29.2 %) eyes in group 2 and the mean change ratio was -1,22 [(-0,86), (-1,55)] dB/year (95% confidence interval) in these eyes. Statistically significant difference was found between the two groups according to the progression of the eyes (p<0.05).
We showed that the chance of stopping the glaucomatous damage depends on the level of IOP obtained by antiglaucomatous treatment. In this case the aim in the treatment of glaucoma patients should be to maintain the lowest IOP.Keywords: POAG, IOP,
Glaucomatous damage progressionTurkiye Klinikleri J Ophthalmol 1999, 8:178-183
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