ISSN: 1300-0365
Dil: Türkçe
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Comparison Of The Effects Of Timolol Maleate, Betaxolol Hciand Carteolol On Intraocular Pressure In The Treatmentof Primary Open Angle Glaucoma
Erdinç AYDIN*, Haluk ERTÜRK**, Bülent YAZICI***
* Araş.Gör.Dr., Uludağ Üniversitesi Tıp Fakültesi Göz Hastalıkları AD,** Prof.Dr., Uludağ Üniversitesi Tıp Fakültesi Göz Hastalıkları AD,*** Uz.Dr., Uludağ Üniversitesi Tıp Fakültesi Göz Hastalıkları AD, BURSA
The aim of this study was to compare the effects of timolol, betaxolol and carteolol upon reducing intraocular pressure in PAAG. Twenty-one eyes of the 14 patients in timolol group, 23 eyes of 15 patients in betaxolol group and 25 eyes of 13 patients in carteolol group were included in this study. Visual acuity, intraocular pressure (IOP), optic nerve head, computerized visual field test were detected. Patients in timolol group were followed up for 37,64 ± 12,74 months, in betaxolol group for 39,93 ± 13,02 months and in carteolol group for 25,15 ± 5,14 months with 3 months interval. During three months, the mean IOP was significantly decreased in timolol and carteolol groups, but not in betaxolol group compared to the baseline. Between 3 and 6 months, reduction in mean IOP was more in carteolol group than in both betaxolol and timolol groups. After six months, mean IOP decrease was not remarkably different among the groups (p>0.05). Reduction in mean IOP in timolol, betaxolol and carteolol groups during the follow-up were 25.12%, 23.59% and 25.79% respectively. It was not significantly different in the groups (p>0.05).
It was found that carteolol was at least as effective as timolol maleate during the initial 6 months period. At the following period in all groups lowering effects of each topical beta- blockers on intraocular pressure were similarly equal.Keywords: Timolol maleate 0.05%,
Betaxolol HCI 0.05%,
Carteolol 2%,
Primary open angle glaucomaTurkiye Klinikleri J Ophthalmol 2000, 9:92-97
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