ISSN: 1300-0365
Dil: Türkçe
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The Effect Of Topical Anesthetic Proparacaine Onnormal Conjunctival Flora
Halit Oğuz*, Elif Oğuz**, Güngör SobacI***, Gönül Aslan****
* Yrd.Doç.Dr., Harran Üniversitesi Tıp Fakültesi Göz Hastalıkları AD,** Ecz., Harran Üniversitesi Tıp Fakültesi Araştırma ve Uygulama Hastanesi Eczanesi, ŞANLIURFA*** Doç.Dr., Gülhane Askeri Tıp Akademisi Göz Hastalıkları AD, Ankara**** Yrd.Doç.Dr., Harran Üniversitesi Tıp Fakültesi Mikrobiyoloji AD, ŞanlIurfa
We investigated the effect of topical anesthetic proparacaine on microorganisms on the normal conjunctival flora. One hundred and forty-four eyes of 72 patients awaiting cataract surgery were included in the study. A commercially available solution of proparacaine, preserved with benzalkonium chloride 0.01%, was instilled to one eye of all subjects while the vehicle solution including the same concentration of preservative in aqueous solution was administered to the other eye. Conjunctival cultures were taken from all eyes before and 15 minutes after the instillation of proparacaine and the vehicle. Of the 144 eyes, 76 (52.8%) had positive-conjunctival cultures with the most commonly isolated organisms being coagulase-negative staphylococci in each group. Of the 76 culture-positive eyes, 40 received proparacaine and 36 the vehicle preparation. Fifteen minutes after the instillation of proparacaine and the vehicle eyedrops, four eyes (10%) and 12 eyes (33,3%) had culture-positive conjunctival smears, respectively. Propara-caine reduced significantly the number of culture-positive eyes (p=0.0003), in contrast of the vehicle (p= 0.21). We conclude that a topical anesthetic, proparacaine reduces microorganisms on the conjunctival flora.Keywords: : Antibacterial, Conjunctival flora, Proparacaine,
Topical anestheticTurkiye Klinikleri J Ophthalmol 2000, 9:175-178
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