ISSN: 1300-0365 Dil: Türkçe
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Radiation Retinopathy After Head And Neck Malignities Radiotherapy
Cenk Zeki Fİkret*, Nil İrem Uçgun**, Hikmet SarIkatİpoğlu***, Hikmet HasIrİpİ****
* Ast.Dr., Ankara Numune Hastanesi 3. Göz Kliniği,** Ast.Dr., Ankara Numune Hastanesi 2. Göz Kliniği,*** Uz.Dr., Ankara Numune Hastanesi 3. Göz Kliniği,**** Uz.Dr., Ankara Numune Hastanesi 3. Göz Kliniği Şefi, ANKARA Purpose: Cancer is the most important health problem in our decade. External radiotherapy is a useful method in head and neck malignites. Our purpose is to find out experimentarilly if radiation retinopathy is a risk after non-ocular, head and neck region radiotherapy and pentoxifylline is an antioxidant agent which is refered to use in this cases.
Materials and Methods: We have 16 New Zeland Rabbits, we seperate them for two groups. 8 of them control group and 8 of them is pentoxifylline group. We applied total 1500 cGy radiation to their head and neck region.
Result: After 30 weeks follow up to both groups, macroscopic and microscopic examinations were done to enucleated globs. There wasn't any pathological findings in both groups.
Conclusion: Glob isn't effected directly when aiming head and neck radiotherapy so radiation retinopathy risks are decreasing. Outhors recommend antioxidant agents when using radiotherapy but we haven't demonstrated their advantages to radiation retinopathy.Keywords: Radiation retinopathy, PentoxifyllineTurkiye Klinikleri J Ophthalmol 2000, 9:234-237
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