ISSN: 1300-0365
Dil: Türkçe
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The Effect Of Pupilla Dilators Used In Outpatient Basis On Intraocular Pressure
Volkan Dayanır*, Özlem Polatlı**, Seyhan B. Özkan***
* Yrd.Doç.Dr., Adnan Menderes Üniversitesi Tıp Fakültesi Göz Hastalıkları AD,** Araş.Gör.Dr., Adnan Menderes Üniversitesi Tıp Fakültesi Göz Hastalıkları AD,*** Doç.Dr., Adnan Menderes Üniversitesi Tıp Fakültesi Göz Hastalıkları AD, AYDIN
This study was planned to investigate the influence of pharmacological agents which are used routinely on outpatient basis for pupil dilation on intraocular pressure (IOP).
We prospectively evaluated 300 patients who had applied to the ophthalmic outpatient clinic. Patients who had diabetes mellitus, glaucoma, glaucoma suspect, previous eye surgery or used pharmacological agents that could alter IOP were excluded. The patients were divided into three main groups which had five subgroups according to age: 21-30, 31-40, 41-50, 51-60, and 61-70 years. Each main group had 100, each subgroup had 20 patients. Main groups were instilled phenylephrine, tropicamide, and cyclopentolate respectively and had IOP measurements before and after half an hour of drop instillation.
Main groups had no difference with regard to age and sex. IOP levels before and after drop instillation for phenylephrine, tropicamide, and cyclopentolate were 14.7 ± 0.3 and 14.8 ± 0.3, 14.3 ± 0.3 and 14.7 ± 0.3, and 14.7 ± 0.3 and 14.6 ± 0.3 respectively. Tropicamide group had significant IOP elevation at half hour after the instillation (p<0.05) that had no relation with age. Other groups did not show any significant change.
Pupillary dilators do not effect IOP markedly. Tropicamide which increased IOP significantly made a rise of 0.4 ± 0.1 mmHg which was clinically insignificant.Keywords: Intraocular pressure, Phenylephrine, Tropicamide, CyclopentolateTurkiye Klinikleri J Ophthalmol 2001, 10:65-67
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