ISSN: 1300-0365
Dil: Türkçe
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Prognostic Factors In Advanced Glaucoma Cases
Nuray Akyol*, Tamer Demİr**
* Doç.Dr., Fırat Üniversitesi Tıp Fakültesi Göz Hastalıkları AD,** Yrd.Doç.Dr., Fırat Üniversitesi Tıp Fakültesi Göz Hastalıkları AD, ELAZIĞ
Objective: To determine the effects of initial clinical signs, the treatment modality, the drop in the intra ocular pressure(IOP) and mean IOP during the follow up period, to progression of the diseases in advanced glaucoma cases.
Institution: University clinic- glaucoma department, retrospective study.
Materials and Methods: Study group consisted of 65 patients who were blind in their one or two eyes because of primary open-angle glaucoma. They were all older than 45 years and followed regularly at least two years. Initial and last visual acuities(VA), IOPs and cup-to-disc ratios, and follow-up periods were taken from the records. The patients were divided into three groups due to treatment modality on which they were put; successful and unsuccessful medical treatment groups, and surgical treatment group. Pressure drops and mean IOPs were calculated and the effects of all these parameters on the losses in VA of the well-eye were analysed statistically with the spss for windows.
Results: Mean age were 71.2 years old and mean follow-up period were 46.4 months in our patients. Out of 65 patients, 50 were blind in one eye (76.9%), and 15 were blind in two eyes (23.1%). For the well-eye, the mean initial VA was 0.51 and the mean loss in VA was 0.1. Age, gender and follow-up time were not found significantly related with the acuity losses. Unsuccessful medical treatment group were significantly different than the other two groups by means of VA loss in well-eye(p<0.05). 34% of the patients with no VA loss had the mean IOP of 15.09 mm Hg during the follow-up. 37% with VA loss less than 0.2 and 29% with VA loss equal or more than 0.2 had the mean pressures of 17.31 and 20.25 mm Hg respectively(p<0.05 and p<0.005). Relations between IOP drop and VA losses were also statistically significant.
Conclusion: The results of this study show that, low intraocular pressure is associated with reduced progression of visual loss, independent of the kind of treatment modality which was used to drop IOP.Keywords: Advanced glaucoma, Treatment alternatives, Prognostic factorsTurkiye Klinikleri J Ophthalmol 2001, 10:158-164
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