ISSN: 1300-0365
Dil: Türkçe
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The Evaluation Of Insulin Dependent Diabetes Mellitus Patients By Visual Evoked Potential And Electroretinography Testing
Filiz Afrashİ*, Süheyla Köse**, Deniz Eğrİlmez***, Günay Haznedaroğlu****, Füsun SaygIlI*****
* Uzm.Dr., Ege Üniversitesi Tıp Fakültesi Göz Hastalıkları AD,** Doç.Dr., Ege Üniversitesi Tıp Fakültesi Göz Hastalıkları AD,*** Asist Dr., Ege Üniversitesi Tıp Fakültesi Göz Hastalıkları AD,**** Prof.Dr., Ege Üniversitesi Tıp Fakültesi Göz Hastalıkları AD,***** Doç.Dr., Ege Üniversitesi Tıp Fakültesi İç Hastalıkları AD, İZMİR
Purpose: To evaluate visual functions of the the patients who have insulin dependent diabetes mellitus (IDDM) without diabetic retinopathy with pattern reversal visual evoked potentials (PVEPs) and flash electroretinography (FERG).
Methods: Twenty patients with IDDM, (aged 19.4± 8.2 years, disease duration of 4.33±2.05 years) were compared with age matched controls using PVEPs and FERG. These results were evaluated t-test statistically.
Results: PVEP examination of IDDM patients revealed that p100 latencies and amplitudes were 102.7±7.2 ms and 4.03±2.0 µV, whereas these values were 99.6±7 ms and 4.83±0.5µV in control group respectively (p>0.05). Regarding FERG, implicit times and amplitudes of the a and b waves for the maximal responses in scotopic condition were found 22.3±2.8ms, 44.8±2.8ms ve 87.4±23.5µV, 295±47.7µV in IDDM group respectively and these values were 21.2±3.2ms, 45.4±2.7ms, 83.2±28µV, 304±70µV in control group. In photopic ERG, implicit times and amplitudes of the a and b waves were 14.7±0.8ms, 31.6±1.5ms ve 35.4±10.6µV , 85±19.5µV respectively in IDDM group and 15.2±1.1ms, 31.4±1.2ms, 34.9±9.3µV, 87±27µV in control group. 30 Hz flicker cone responses were 70±10µV in IDDM group and 73±9.2µV in control group. Considering the all values related to FERG, there is no significant different between in both groups statistically (p>0.05).
Conclusions: It is worth to evaluate the functional properties of the diabetic retina with objective methods, such as PVEPs and FERG. However, in our study we could not determine any significant differences in parameters of PVEPs and FERG in patients with short duration of IDDM without diabetic retinopathy.Keywords: Insulin dependent diabetes mellitus, Visual evoked potential, Flash electroretinographyTurkiye Klinikleri Oftalmloji 2001, 10:153-157
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