ISSN: 1300-0365
Dil: Türkçe
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Effect Of Midazolam And Pethidine On Intraocular Pressure,oxygen Saturation And Amnesia In Cataract Surgery
Aysel PELİT*, Perran POYRAZ**, Nezih AYDOĞAN***, Pınar AYDIN****
* Yrd.Doç.Dr., Başkent Üniversitesi Tıp Fakültesi Göz Hastalıkları AD,** Yrd.Doç.Dr., Başkent Üniversitesi Tıp Fakültesi Anestezi AD,***. Uz.Dr., Başkent Üniversitesi Tıp Fakültesi Göz Hastalıkları AD, ADANA****Prof.Dr., Başkent Üniversitesi Tıp Fakültesi Göz Hastalıkları AD, ANKARA
Purpose: Investigation of the effect of a single dose of midazolam and pethidine on amnesia, intraocular pressure (IOP) and oxygen saturation which was given for sedation in patients undergoing cataract surgery.Institution: Başkent University School of Medicine, Department of Ophthalmology.Methods: Forty patients, aged 50-85, were randomly assigned to two groups. In group I (n: 20), a single dose of 0.03 mg/kg of midazolam and in group II (n: 20), a single dose of 0.5 mg/kg of pethidine were given intravenously. Measurements of IOP and oxygen saturation were taken at baseline and 2, 5, 10 and 15 minutes after sedation. After the operation patients were asked if they had remembered the peribulbar injection.Results: Compared with the baseline values, IOP was significantly lower in both groups 2, 5, 10 and 15 minutes after the administration of sedatives. Oxygen saturation decreased in 2, 5 and 10 minutes in group I and in 2 minutes in group II after the intravenous sedation. Oxygen saturation reached baseline levels in 15 minutes in-group I and in 5 minutes in group II after the intravenous sedation. Amnesia related to the peribulbar injection was significantly different among the groups. In group I 90 % and in group II 20 % of the patients amnesia.Conclusion: Intravenous sedation with low dose midazolam may be the drug of choice in particular because of its amnesic effect in cataract surgery.Keywords: Sedation, Midazolam, Pethidine, Amnesia, Intraocular pressureTurkiye Klinikleri J Ophthalmol 2002, 11:150-153
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