21-11-2008

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ISSN: 1300-0365
Dil: Türkçe

 

ORIGINAL RESEARCH ARTICLES


The Comparatively Evaluation Of Early Clinical Retinopathy Findings By Colour And Achromatic Perimetry In Type 2 Diabetes Mellitus

Dr.Erdinç AYDIN,a Dr.Yüksel TOTAN,b Dr.Mutlu Cihan DAGLIOĞLU,b Dr.Tongabay CUMURCUb
aGöz Hastalıkları AD, Gaziosmanpaşa Üniversitesi Tıp Fakültesi TOKATbGöz Hastalıkları AD, İnönü Üniversitesi Tıp Fakültesi, MALATYA



Objective: We aimed to comparatively evaluate the possible cent-ral visual field changes prior to the development of clinically detectable retinopathy in type 2 diabetes with colour perimetric tests and achromatic perimetric tests. Material and Methods: Forty-seven patients with type 2 diabetes, survivor of Ophthalmology and Endocrinology Clinics, İnönü University Faculty of Medicine, were included in the study. The central 30-2 threshold tests (blue-on-yellow (B/Y) and white-on-white (W/W)) by Humphrey Field Analyzer (HFA-750) were applied to both eyes in 26 patients with no retinopathy and 21 with mild retinopathy. Twenty- four eyes of 12 healthy subjects of similar age and gender distribution served as control group. Demographic characteristics, blood HbA1c levels, mean deviation (MD) and pattern standard deviation (PSD) values as objective perimetric indices were compared among the groups by statistical methods.Results: There was no difference between the groups in age and gender distribution. The mean duration of diabetic disease was significantly (P=0.001) longer in mild background retinopathy group compared to the no retinopathy group. There were a significant decrease in MD values and increase in PSD values of the chromatic and achromatic visual field tests in diabetic groups compared to the control group (P<0.05). Decrease in MD values and increase in PSD values of the chromatic visual field tests were found remarkable (p<0.05), but were not detected significant (p=0.095) in the achromatic tests in mild background group compared to no retinopathy group. The duration of the disease. and blood HbA1c levels were not found significantly correlated with MD and PSD values in diabetic patients. The achromatic and chromatic visual field defects in the diabetic patients were often localized at the superior quadrants and between 20° - 30°.Conclusion: Prior to clinically detectable retinopathy, retinal sensitivity loss and visual field defects may develop in type 2 diabetic patients. Colour automated perimetry (B/Y) is a more sensitive method in early detection of the preclinical visual field defects than achromatic automated perimetry (W/W) in diabetic retinopathy.

Keywords: Type 2 diabetes mellitus, retinopathy, achromatic perimetry, chromatic perimetry

Turkiye Klinikleri J Ophthalmol 2004, 13:129-133

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