ISSN: 1300-0365
Dil: Türkçe
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Conjunctival Cytology In Patients Wearing Soft Contact Lenses
Sevin SÖKER ÇAKMAK*, Kaan ÜNLÜ**, Yusuf NERGİS***, Candan KARACA****,Sevda İPEK*****, Yıldırım Bayezıt ŞAKALAR******
* Yrd.Doç.Dr., Dicle Üniversitesi Tıp Fakültesi Göz Hastalıkları AD,** Doç.Dr., Dicle Üniversitesi Tıp Fakültesi Göz Hastalıkları AD,*** Prof.Dr., Dicle Üniversitesi Tıp Fakültesi Histoloji ve Embrioloji AD, DİYARBAKIR**** Op.Dr., Ünye Devlet Hastanesi Göz Kliniği, ORDU***** Arş.Gör.Dr., Dicle Üniversitesi Tıp Fakültesi Histoloji ve Embrioloji AD,****** Arş.Gör.Dr., Dicle Üniversitesi Tıp Fakültesi Göz Hastalıkları AD, DİYARBAKIR
Objective: To determine the alteration on the conjunctival epithelia in symptomatic and asymptomatic patients who wear soft contact lenses.Material and Methods: 50 soft contact lens wearers, controlled periodically, in our contact lens unit were included in this study. Tear film break up time, basal Schirmer's test and impression cytology samples of conjunctiva were obtained for all cases. Materials were stained and graded according to the Nelson's grading scale.Results: Of the patients wearing contact lenses, 40% did not have any contact lens-related complaints, whereas 60% had some complaints related to contact lens intolerance. Goblet cell density was 242.3 ± 44.6 cells /mm² in the group without complaints, and 168.8 ± 33 cells/mm² in the group with intolerance. When epithelial cell morphology was graded according to the system described by Nelson, specimens from the asymptomatic group revealed 44% grade 0, 26% grade 1, 26% grade 2 and 4% grade 3. Whereas of the symptomatic gruop revealed 0% grade 0, 22% grade 1, 30% grade 2, and 48% grade 3. Statistically significant differences were observed between the symptomatic group and the asymptomatic group with regard to each group's grade (p < 0.001).Conclusion: Prevalence and severity of cytological alteration is more in symptomatic contact lens wearers. Asymptomatic soft contact lens wearers may also show severe cytological changes.Keywords: Impression cytology, Conjunctiva, Contact lens, SymptomTurkiye Klinikleri J Ophthalmol 2004, 13:73-76
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