ISSN: 1300-0365
Dil: Türkçe
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Keratoprosthesis Surgery
Dr. Tolga KOCATÜRK,a Dr. Claes H. DOHLMANb
aGöz Hastalıkları AD, Adnan Menderes Üniversitesi Tıp Fakültesi, AYDINbMassachusetts Göz ve Kulak Reviri, Göz Hastalıkları Kliniği, Harvard Üniversitesi Tıp Fakültesi, BOSTON
Corneal transplantation (i.e., penetrating keratoplasty), is the most common treatment for severe corneal disease or trauma leading to opacification of the cornea. However, the prognosis of standard corneal transplantation remains poor for patients diagnosed with ocular cicatrial pemphigoid, Stevens-Johnson syndrome, end-stage dry eyes, severe chemical burns and those with repeated failure of corneal transplantation.
Keratoprosthesis (KPro), an artificial cornea, provides a clear window in the clouded cornea. KPro does not opacify and can not vascularize like human donor corneas. Thus, KPro implantation is an alternative to expected or repeated unsuccessful corneal transplantation and has increased about 20-fold during last decade. The primary reason for this increased acceptance has been the sharp reduction in complications, such as tissue melt, necrosis, extrusion, endophthal-mitis, etc-outcomes which were common just a few decades ago. KPro gives hope to the perhaps 10-12 million people worldwide who are blind from corneal disease today and who presently have little chance of any lasting improvement with conventional methods.Keywords: Corneal transplantation; dry eye syndromeTurkiye Klinikleri J Ophthalmol 2007, 16:47-55
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