ISSN: 1300-0365
Dil: Türkçe
|
|
|
The Relationship Between Venous Stasis Retinopathy And Hyperhomocysteinemia: Case Report
Dr. Şansal GEDİK,a Dr. Leyla ERKANLI,a Dr. Gürsel YILMAZ,a Dr. O. İlhami ÖZCEBE,b Dr. Yonca A. AKOVAa
aGöz Hastalıkları AD, Başkent Üniversitesi Tıp Fakültesi,bİç Hastalıkları AD, Hematoloji Ünitesi, Hacettepe Üniversitesi Tıp Fakültesi, ANKARA
Twenty nine-years-old male patient was examined for blurred vision in the right eye. Ophthalmologic examination revealed visual acuities of 20/20 in both eyes and intraocular pressure measurements of 14 mm Hg, bilaterally. Pupil diameter was 3 mm, direct and indirect light reflexes were positive and there was no relative afferent pupillary defect. Ishihara color vision test and anterior segment slit-lamp examination were within normal limits. Fundoscopy showed blurred optic disc margins, increased vascular tortuosity, congestion of retinal veins and hemorrhage in all retinal quadrants. In fundus fluorescein angiography, hypoflorescent areas were seen in sites of hemorrhage but there was no sign of retinal ischemia. The patient was investigated for the etiology of central retinal vein occlusion. Folic acid and homocystein levels were 5.09 ng/ml (3-17) and 15 µmol/L (6-15), respectively and the patient was heterozygous for methylenetetrahydrofolate reductase (MTHFR) mutation. The etiology of venous stasis retinopathy was considered to be hyperhomocysteinemia. After folic acid treatment, total homocystein level decreased from 15 µmol/L to a safe value of 8.9 µmol/L. There was no progression in venous stasis retinopathy and retinal venous congestion was regressed. In this case report, we aimed to discuss the possible etiology of venous stasis retinopathy, hyperhomocysteinemia and its treatment in the young age group.Keywords: Hyperhomocysteinemia; retinal vein occlusion; folic acidTurkiye Klinikleri J Ophthalmol 2007, 16:136-140
|
|
|
|
|
