ISSN: 1300-0365
Dil: Türkçe
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ORIGINAL RESEARCH ARTICLES |
16 Years In The Management Of Microbial Keratitis
Dr. Safiye YILMAZ, aDr. Ilgın ÖZTÜRK, aDr. Melih TÜRE, aDr. Ahmet MADENa
aGöz Kliniği, İzmir Atatürk Eğitim ve Araştırma Hastanesi, İZMİR
Objective: To compare the results of the empirical treatment for the hospitalized patients with microbial keratitis and the treatment after the culture and smear of microbial keratitis in the preceding 16 years and to analyze the relationship between the risk factors and response of the treatment. Material and Methods: Medical records were reviewed for all patients with clinically diagnosed microbial keratitis presenting at our clinic from January 1990 to December 2005 retrospectively. Risk factors, microbial isolations and responses to the treatment were analyzed.
Results: Microbial keratitis was diagnosed in 620 eyes of 250 female and 370 male (mean age, 54.13 ±20.06 years). Identification of pathogens from the cultures was achieved for 225 eyes (36.2%), and included gram-negative (8.9%) and gram-positive organisms (68.8%) and fungi (22.3%). Staphylococcus epidermidis were the most commonly isolated organisms (26.6%) of all positive cultures. Ocular trauma was the most common predisposing factor (26.6%). Microbial keratitis was cured in 414 (66.7%) patients with empirical treatment and cured in 76 patients after changing treatment and anatomical and/or functional integrity was achieved in 100 patients after the additional surgical treatment. Evisceration was performed in 30 patients with spontaneous perforation. Conclusıon: Keratitis is the most common source of the monocular blindness in whole world. As early diagnosis and prompt treatment are important prognostic indicators in microbial keratitis, it is important to analyze the microbiological results in relation with corneal findings and the history of the paKeywords: Keratitis, therapy, risk factors, treatment outcomeTurkiye Klinikleri J Ophthalmol 2008, 17:1-6
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